Abstract: This paper proposes a management system of distributed databases in the background of the large-scale application of databases. The system uses the middleware of Amoeba to realize the management of server cluster. It utilizes Amoeba to gather and modify the information of servers， to configure the parameters of Amoeba servers and MySQL database servers, load balancing, the separation rule of read and write, and data segmentation. Administrators can use this system to master the state of servers and avoid tedious operation. At last, the experiment shows that it can effectively configure the parameters to manage a large number of servers.
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Key words: distributed database, Amoeba, data segmentation, database management